I have a recently adopted cat who spent 9 months in a shelter and lost 3 pounds then. After adoption, she was diagnosed with Inflammatory Bowel Disease. While waiting for test results to come back to see if she had Exocrine Pancreatic Insufficiency, I decided to try her on Bio-Case V digestive enzymes. That seemed to help her stop losing weight, but she wasn't gaining. The test results did not indicate EPI, but I decided to keep her on digestive enzymes. I switched to Total Zymes and within a few days, her stool was much improved. Darker and smaller, indicating nutrients were getting absorbed.She started to gain weight. She also has Small Intestinal Bacterial Overgrowth. From what I read, it sounded like L-Acidophilus as a probiotic, along with digestive enzymes, might help. Between the Total Zymes and L-Acidophilus, I hear much less in the way of stomach noises and burping. Good appetite and weight gain of 8 oz. in 9 days! Do be aware that the body needs to go thru a period of purging once you find a product like Total Zymes that works. There was a period of several days where her appetite and weight dropped again. I was afraid at first that it wasn't working, but then I read that the body has to get the gunk out and this can result in some short term stomach upset. I've read this can last from 1-3 weeks. Glad I kept her on Total Zymes, she's gained weight nicely and is finally doing well.Total Zymes is plant-based, rather than animal based. Some say animal-based digestive enzymes may not hold up against stomach acid. Another positive - this product is tasteless, so my cat is fine with sprinkling it on her food. You only distribute 1/4 teaspoon over 8 ounces of food, so you're not putting on alot.